Prospective Measurement of Blood Pressure and End Tidal Carbon Dioxide Content Effects on Venous Sinus Caliber and Pressures in Patients With Idiopathic Intracranial Hypertension Undergoing Stenting
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Venous Sinus Pressures
研究概览
简要总结
The purpose of this study is to further elaborate the role of both arterial blood pressure and end-tidal carbon dioxide concentration on measured venous pressures.
详细描述
To prospectively evaluate the effect of changes in end-tidal carbon dioxide and arterial blood pressure on venous sinus pressure measurements in patients undergoing venous sinus stenting under general anesthesia. Venous sinus pressure measurements will increase with increases in both arterial blood pressure and end-tidal carbon dioxide concentrations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults determined to be candidates for venous sinus stenting
排除标准
- 未提供
研究组 & 干预措施
Group A
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group A: Initial Recording: Mean Arterial Pressure 60-80 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 100-80 mmHg, End tidal CO2 38-40 mmHg.
干预措施: Venous Sinus Stenting (Procedure)
Group A
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group A: Initial Recording: Mean Arterial Pressure 60-80 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 100-80 mmHg, End tidal CO2 38-40 mmHg.
干预措施: Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range) (Other)
Group A
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group A: Initial Recording: Mean Arterial Pressure 60-80 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 100-80 mmHg, End tidal CO2 38-40 mmHg.
干预措施: Adjustment to Mean Arterial Pressure (100-110 mmHg range) (Other)
Group B
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group B: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 60-80 mmHg, End tidal CO2 38-40 mmHg,
干预措施: Venous Sinus Stenting (Procedure)
Group B
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group B: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 60-80 mmHg, End tidal CO2 38-40 mmHg,
干预措施: Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range) (Other)
Group B
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group B: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 60-80 mmHg, End tidal CO2 38-40 mmHg,
干预措施: Adjustment to Mean Arterial Pressure (60-80 mmHg range) (Other)
Group C
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group C: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 24-26 mmHg, Subsequent Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg,
干预措施: Venous Sinus Stenting (Procedure)
Group C
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group C: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 24-26 mmHg, Subsequent Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg,
干预措施: Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range) (Other)
Group C
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group C: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 24-26 mmHg, Subsequent Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg,
干预措施: Adjustment to Mean Arterial Pressure (100-110 mmHg range) (Other)
Group D
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group D: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 100-100 mmHg, End tidal CO2 24-24 mmHg,
干预措施: Venous Sinus Stenting (Procedure)
Group D
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group D: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 100-100 mmHg, End tidal CO2 24-24 mmHg,
干预措施: Adjustment to Mean Arterial Pressure (100-110 mmHg range) (Other)
Group D
Adult patients determined to be candidates for venous sinus stenting.
End tidal CO and Mean Arterial Pressure will be adjusted to the following parameters during the intervention:
For Group D: Initial Recording: Mean Arterial Pressure 100-110 mmHg, End tidal CO2 38-40 mmHg, Subsequent Recording: Mean Arterial Pressure 100-100 mmHg, End tidal CO2 24-24 mmHg,
干预措施: Adjustment to end-tidal carbon dioxide concentrations (24-26 mmHg range) (Other)
结局指标
主要结局
Venous Sinus Pressures
时间窗: After intervention, up to 5 minutes
Venous Sinus Pressures
时间窗: Baseline
次要结局
- Venous Sinus Diameter(After Intervention, up to 5 minutes)
- Venous Sinus Diameter(Baseline)