JPRN-UMIN000011861
Completed
Phase 2
A phase II study of preoperative concurrent chemoradiotherapy with TS-1/ Oxaliplatin in patients with locally advanced rectal cancer(PerSeUS-RC01) - A phase II study of neoadjuvant SOX + RT for locally advanced rectal cancer(PerSeUS-RC01)
PerSeUS:Perpetual Study estimated-by United Sections in Gifu0 sites40 target enrollmentSeptember 25, 2013
Conditionslocally advanced rectal cancer
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- locally advanced rectal cancer
- Sponsor
- PerSeUS:Perpetual Study estimated-by United Sections in Gifu
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) History of Severe drug allergy 2\) Active infections (over 38\.0 degree) 3\) Severe concurrent disease (interstitial pneumonitis or pulmonary fibrosis, poorly controlled diabetes, renal failure or hepatic failure) 4\) Severe aberration of electrocardiogram, schemic heart disease, arrhythmia, cardiac infarction or heart failure. 5\) Sensory neuropathy 6\) Watery diarrhea 7\) Massive pleural effusion or ascites 8\) Active double cancer (synchronous double cancer or asynchronous double cancer with disease\-free duration of 5 years or less) 9\) Pregnant females, possibly pregnant females, females wishing to become pregnant and nursing mothers. Males that are currently attempting to produce a pregnancy 10\) Current use of flucytosine 11\) Positive hepatitis\-B antigen 12\) Physician concludes that the patient's participation in this trial is inappropriate.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Phase 2
A phase II study of preoperative concurrent chemoradiation therapy for patients with locally advanced rectal cancerectal cancerJPRN-UMIN000004104Hamamatsu University School of Medicine, Second department of Surgery30
Recruiting
Phase 2
A Phase II study of preoperative concurrent chemoradiotherapy with TS-1 in patients with locally advanced lower rectal cancer.ocally-advanced lower rectal cancerJPRN-UMIN000006242ara Hospital Kinki University Faculty of Medicine20
Completed
Phase 2
A phase II study of preoperative concurrent chemoradiotherapy with cisplatin and docetaxel in patients with locally advanced non-small-cell lung cancerresectable locally advanced non small cell lung cancerJPRN-UMIN000000599Setouchi Lung Cancer Group1
Active, not recruiting
Phase 1
Multicenter phase II study of preoperative chemoradiotherapy with CApecitabine plus Temozolomide in patients with MGMT silenced and microsatellite stable locally Advanced RecTal Cancer: the CATARTIC triallocally advanced rectal cancer (LARC)MedDRA version: 20.0Level: HLTClassification code: 10010023Term: Colorectal neoplasms malignant Class: 10029104Therapeutic area: Diseases [C] - Neoplasms [C04]CTIS2024-513931-26-00Fondazione IRCCS Istituto Nazionale Dei Tumori21
Active, not recruiting
Phase 1
Study on the association of radiotherapy with capecitabine and temozolomide followed by surgery in patients with locally advanced rectal cancerEUCTR2021-002325-18-ITFONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI21