Assessing the effect of brimonidine gel on the redness remained after pimples
Phase 3
- Conditions
- Post-acne erythema.Other acneL70.8
- Registration Number
- IRCT20140212016557N11
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients between 18 and 45 years of age
Post-acne erythema after successful treatment of acne vulgaris
Exclusion Criteria
pregnancy
lactation
depression
cerebral or coronary artery insufficiency
Raynaud’s phenomenon
orthostatic hypotension
thromboangiitis obliterans
scleroderma
Sjögren’s syndrome
severe or unstable cardiovascular disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinician score of post-acne erythema. Timepoint: Before intervention, 4 and 8 weeks after starting intervention, and 1 months after treatment cessation. Method of measurement: 5-point clinical score, defined as: 0=clear with no erythema, 1 = almost clear or slight redness, 2 = mild or definite redness, 3 = moderate or marked redness, 4 = severe or fiery redness.
- Secondary Outcome Measures
Name Time Method Skin erythema index. Timepoint: Before intervention, 4 and 8 weeks after starting intervention, and 1 months after treatment cessation. Method of measurement: Dermacatch instrument.;Patient self-assessment of post acne erythema treatment. Timepoint: 4 and 8 weeks after starting intervention, and 1 months after treatment cessation. Method of measurement: 4-point patient assessment of treatment result expressedas: a. No improvement, b. Mild improvement, c. Good improvement, d. Excellent improvement.;Quality of life. Timepoint: before intervention and 1 months after cessation of treatment. Method of measurement: Dermatology Life Quality index questionnaire Persian version.