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Characteristics of biomarker on dermal sensitization for myocardial ischemia-reperfusion injury

Early Phase 1
Conditions
myocardial ischemia reperfusion injury
Registration Number
ITMCTR2024000180
Lead Sponsor
the Affiliated Hospital of Shaanxi University of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

MIRI patients:
(1) meeting the diagnostic criteria of non-ST elevation acute coronary syndrome in 2023 ESC Guidelines for the management of acute coronary syndromes.
(2) received percutaneous coronary intervention within a week.
(3) aged 18 to 85 years.
(4) willing to participate in this study, and sign on informed consent.
Healthy subjects:
(1) received a health examination within a week, and confirmed to be in good health.
(2) aged 18 to 85 years, and matching the MIRI patients.
(3) willing to participate in this study, and sign on informed consent.

Exclusion Criteria

(1) diagnosed as ST-elevation myocardial infarction, with persistent ST-segment elevation or ST-segment elevation equivalents on electrocardiogram.
(2) combined with disorders of rhythm, disorders of the heart, muscles, valves, and pericardium, and peripheral vascular disease.
(3) suffering from neoplastic disorders, hematopoietic disorders, disorders of hemostasis, infectious diseases, immune-mediated, inflammatory, and rheumatologic disorders.
(4) combined with fever.
(5) suffering from psychiatric disorders, and unable to cooperate.
(6) participating in any other study using an unapproved drug within 3 months.

Study & Design

Study Type
Observational study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
mRNA;
Secondary Outcome Measures
NameTimeMethod
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