Efficacy of sodium bicarbonate buffered lidocaine hydrochloride for local anaesthesia in intra-alveolar extraction of mandibular molars: a randomised controlled double-blind study

myself0 sites220 target enrollmentOctober 23, 2023

Overview

No summary available.

Registry

who.int

Start Date

October 23, 2023

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

myself

•1\.Patients requiring intra\-alveolar extraction of mandibular first and/or second molar.
•2\.Patients between the ages of 18\-60years
•3\.Patients with American Society of Anesthesiologists (ASA) I and II health status at the time of treatment.

•1\.Patients with known underlying systemic diseases such as bleeding dyscrasia and immunosuppression \[e.g. uncontrolled diabetes mellitus, clotting disorder, hyperthyroidism, arteriosclerosis, cardiac insufficiency, other cardiovascular disorders, Auto\-immunodeficiency Syndrome (AIDS)].
•2\.Patients with allergy or hypersensitivity to any of the constituents of the anaesthetic solution in the surgical protocol.
•3\.Patients on anticoagulants
•4\. Patients taking any medications that would alter pain perception (opioids, synthetic cannabinoids, hallucinogens, antidepressants, anticonvulsants, methamphetamine, cocaine, benzodiazepines, 3,4\-Methylenedioxymethamphetamine, Serotonin\-Norepinephrine Re\-uptake Inhibitors)
•5\.Patients who are current smokers and chronic alcoholics for more than two months
•6\.Patients with cognitive or physical impairment
•7\.Pregnant women and/or breastfeeding mothers
•8\.Inability to give informed consent
•9\.Teeth with abscess at the time of extraction