Effects of Exercise on Glypican4,CTRP3,5 and RBP4 Levels and Circulating Levels of These Adipokines in the Subjects With or Without Metabolic Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- The changes of circulating glypican4 levels after 3 months exercise
研究概览
简要总结
Glypican4, CTRP3, CTRP5 are emerging novel adipokines mediating obesity and inflammation related disorders. RBP4 and adiponectin are well known important adipokines. Therefore, we examine the circulating levels of theses adipokines in the subjects with or without metabolic syndrome. Furthermore, we tried to clarify the effect of exercise on the circulating these adipokines.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Women between 30 and 60 years of age who had a body mass index (BMI) more than 25 kg/m2
- •The subjects of metabolic syndrome and age, gender matched non metabolic syndrome among the participants of Korean SO Study (KSOS) study, which is an ongoing epidemiologic study supported by the Korea Science and Engineering Foundation
排除标准
- •participants had a history of cardiovascular disease
- •any type of diabetes
- •stage 2 hypertension
- •malignant disease, severe renal, or hepatic disease
- •Subjects taking medications that might affect body weight or body composition
研究组 & 干预措施
Exercise
obese women who are volunteers for the 3 months exercise programs
干预措施: 3months Exercise (Behavioral)
结局指标
主要结局
The changes of circulating glypican4 levels after 3 months exercise
时间窗: baseline and 12weeks
The changes of circulating CTRP3 levels after 3 months exercise
时间窗: baseline and 12weeks
The changes of circulating CTRP5 levels after 3 months exercise
时间窗: baseline and 12weeks
The changes of circulating RBP4 levels after 3 months exercise
时间窗: baseline and 12weeks
The changes of circulating adiponectin levels after 3 months exercise
时间窗: baseline and 12weeks
次要结局
- Circulating glypican4 levels in the subjects with or without metabolic syndrome(baseline)
- Circulating CTRP3 levels in the subjects with or without metabolic syndrome(baseline)
- Circulating CTRP5 levels in the subjects with or without metabolic syndrome(baseline)
- Circulating RBP4 levels in the subjects with or without metabolic syndrome(baseline)
- Circulating adiponectin levels in the subjects with or without metabolic syndrome(baseline)