Willingness to Participate in Clinical Trials Among Black and African Americans
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Researcher-Subject Relations
- Sponsor
- Harvard University
- Enrollment
- 323
- Locations
- 1
- Primary Endpoint
- Willingness to Participate in a Clinical Trial
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Despite significant racial disparities in health outcomes, racial minority groups in the United States are not adequately represented in clinical trials, and clinical trial results published in major medical journals often underreport racial demographic data of participants. Lack of diversity in clinical trials threatens the generalizability of study results and reduces the ability of minority groups to benefit from medical advancement and innovation. Prior studies show that Black men are more likely to engage in preventive services when there is racial concordance with their healthcare provider. There is minimal literature about how racial concordance or diversity in clinical trial leadership impacts study enrollment. This project examines whether patients' willingness to participate in randomized clinical trials differs based on the characteristics of the investigator.
Detailed Description
We plan to recruit subjects and randomly assign them to one of four treatments. In each treatment arm, the subject will view a photograph of a real NIH investigator. We experimentally vary treatment along two dimensions: whether the sender is Black or white and whether the sender is male or female. Our primary aim is to assess whether the subject's stated willingness to participate in a clinical trial led by the investigator. Our secondary aim is to assess whether the subject is a more objective measure of interest in signing up for information on other clinical trials. To assess mechanisms, we will ask the respondent to rate the subject's perceived trustworthiness and quality of the investigator. In addition, we will also assess the subject's perceived attractiveness and age of the investigator as well as the subject's risk aversion, altruism, time preference, and general trust.
Investigators
Marcella Alsan
Professor of Public Policy
Harvard University
Eligibility Criteria
Inclusion Criteria
- •participant identifies as Black or White
Exclusion Criteria
- •participant doesn't identify as Black or White
- •younger than 25 years old, older than 64
Outcomes
Primary Outcomes
Willingness to Participate in a Clinical Trial
Time Frame: February 17, 2022 - February 19, 2022
Survey respondents' willingness to participate in a vaccine clinical trial led by the person in the photo.