Mother-Infant Psychoanalysis Project of Stockholm (MIPPS)- Follow-up at 4½ Years

Early Phase 1

• Conditions: Mother-child Relationship Disturbances

• Registration Number: NCT01087112
• Lead Sponsor: Karolinska Institutet

Brief Summary

An RCT comparing mother-infant psychoanalytic treatment (MIP) with Child Health Centre care in cases of mother-infant relationship disturbances was performed on 80 cases in Stockholm 2005-2008. The infants were \< 18 months at interview #1. At 6 months follow-ups, significant effects were shown in favour of MIP on maternal sensitivity (EAS), depression (EPDS), and relationship qualities PIR-GAS). This study will evaluate effects at a child age of 4½ years; to evaluate the longterm effects of MIP and CHild Health Centre care, and to better validate results on children who now have reached an age where they can participate more actively in evaluations.

Detailed Description

DESIGN

The 71 dyads remaining from the MIPPS-01 study will be interviewed when the children have reached 4½ years, in order to evaluate the long-term intervention effects of MIP treatments delivered by psychoanalysts at the Infant Reception Service of the Swedish Psychoanalytic Society and of the usual treatments of infants and children in Sweden implying contact with nurses at Child Health Centres.

INSTRUMENTS

Mother-report questionnaires; the Ages and Stages Questionnaire:Social-Emotional (ASQ:SE; Squires et al., 2002), the Edinburgh Postnatal Depression Scale (EPDS; Cox et al., 1987), the Swedish Parental Questionnaire (SPSQ; Östberg et al., 1997) and the Strengths and Difficulties Questionnaire (SDQ; Goodman, 1997).

Independently rated video-taped mother-child interactions: the Emotional Availability Scale (EAS; Biringen, 1998).

Assessment of the general functioning of the child : Children's Global Assessment Scale (Shaffer et al 1983).

Assessment of the child's cognitive functioning: Wechsler Preschool and Primary Scale of Intelligence (WPPSI, Wechsler, 2005).

Assessment of the child's social and emotional functioning: Story Stem Attachment Profile (SSAP, Hodges et al., 2003). Machover Draw-a-Person Test (Blomberg \& Cleve, 1997)

Study Timeline

• Status Verified: 2009-12
• Study Start: 2009-12
• Study First Submitted: 2009-12-29
• Study First Submitted QC: 2010-03-15
• Last Update Submitted: 2010-03-15
• Study First Posted: 2010-03-16
• Last Update Posted: 2010-03-16
• Primary Completion: 2012-06
• Study Completion: 2013-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 71

Inclusion Criteria

• The mother expressed significant concerns about one or more of the following domains: herself as a mother, her infant's well-being, or the mother-baby relationship (this was operationalized as a score < 80 ("perturbed relation") on the PIR-GAS or, alternatively, > 2.5 on the SPSQ).
• Infant of any gender, age below 18 months.
• Duration of worries exceeding two weeks.
• Domicile in Stockholm.
• Reasonable mastery of Swedish.

Exclusion Criteria

• Maternal psychosis according to DSM-IV, to an extent precluding collaboration.
• Substance dependence according to DSM-IV, to an extent precluding collaboration.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Child functioning: Children's Global Assessment Scale	At followup interview
Maternal depression: Edinburgh Postnatal Depression Scale	At followup interview

Secondary Outcome Measures

Name	Time	Method
Maternal distress: Symptom Check List - 90	At followup interview
Maternal stress: Swedish Parental Stress Questionnaire	At followup interview
Child functioning: Ages and Stages Questionnaire:Social Emotional	At followup interview
Child functioning: Strengths and Difficulties Questionnaire	At followup interview
Child cognitive functioning: Wechsler's Preschool and Primary Scales of Intelligence	At followup interview
Child's social and emotional functioning: Story Stem Attachment Profile	At followup interview
Child's social and emotional functioning: Machover Draw-a-Person test	At followup interview

Trial Locations

Locations (1)

Department of Women's and Children's Health, Child and Adolescent Psychiatry Unit, Karolinska Institutet; 🇸🇪 Stockholm, Sweden