Use of Infrared Spectroscopy in Fast Septic Arthritis Diagnosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 360
- 试验地点
- 6
- 主要终点
- Diagnosis of the cause of joint effusion
研究概览
简要总结
To study the diagnostic performance of infrared spectroscopy on fresh synovial fluids in early septic arthritis diagnosis in patients with acute joint effusion
详细描述
Diagnosis of a joint effusion is frequently a medical emergency, especially when septic arthritis is suspected. Septic arthritis diagnosis relies on microscopic and bacteriological analysis of synovial fluid obtained by arthrocentesis. Direct microscopic examination can be made within 2 to 12 hours but it is negative in about 50 % of the cases. It is necessary to wait 72 hours to obtain the result of the culture and reasonably rule out the diagnosis of septic arthritis. A method of establishing an immediate etiological diagnosis could improve the care of patients with joint effusion that is a therapeutic emergency and justify a hospitalization and a parenteral antibiotic therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients over 18 year old
- •patients with an acute arthritis defined by an evolution of less than 6 weeks
- •patients benefiting from joint fluid puncture for diagnostic purposes in the rheumatology hospitals participating in the study
- •patients who received information about the protocol and have not expressed opposition to participate
排除标准
- •patients opposing the study
- •protected major (safeguard justice, trusteeship and guardianship) and persons deprived of liberty
结局指标
主要结局
Diagnosis of the cause of joint effusion
时间窗: Up to 7 days (time to perform Spectroscopy and collect laboratory results)
The final diagnosis of the cause of joint effusion is made by the clinician based on the clinical and laboratory data : septic arthritis or other causes of arthritis
次要结局
- Number of days of hospitalization(Up to 2 months (time to collect data on hospitalization duration and antibiotic therapy duration))
- Total dose of antibiotics(Up to 2 months (time to collect data on hospitalization duration and antibiotic therapy duration))