NCT01271413已完成2 期
Effects of Cognitive Training in Methadone Maintenance Patients
适应症
干预措施
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 134
- 试验地点
- 1
- 主要终点
- Working Memory
研究概览
简要总结
This research is being done to learn if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking. The study will compare the effects of different versions of the computer tasks. It also will compare the task performance of different groups of people.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18-55
- •in methadone maintenance or healthy volunteers
排除标准
- •Axis I disorder (except substance abuse and dependence in methadone maintenance patients)
- •severe cognitive impairment
- •serious untreated medical condition
研究组 & 干预措施
Adaptive cognitively stimulating activities
Experimental
干预措施: Computerized cognitively stimulating activities (Behavioral)
Non-adaptive cognitively stimulating activities
Active Comparator
干预措施: Computerized cognitively stimulating activities (Behavioral)
结局指标
主要结局
Working Memory
时间窗: baseline, 7 weeks
Change in maximum number of digits correctly recalled in Digit Span Backwards task, from baseline to 7 weeks
次要结局
- Episodic Memory(baseline, 7 weeks)
- Trail-making(baseline, 7 weeks)
- go/No-go(baseline, 7 weeks)
- Addiction Severity Index(baseline, 7 weeks)
- Delay Discounting(baseline, 7 weeks)
- Digit Symbol Substitution Test(baseline, 7 weeks)
研究者
Miriam Mintzer
Associate Professor
Johns Hopkins University
研究点 (1)
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