Effects of Multimodal Physical Therapy on Pain, Disability, H-reflex, and Diffusion Tensor Imaging Parameters in Patients With Lumbosacral Radiculopathy
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Lumbosacral Radiculopathy
- Sponsor
- Cairo University
- Enrollment
- 14
- Locations
- 1
- Primary Endpoint
- Disability
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Purposes of the study
To investigate the effect of Multimodal Physical Therapy on pain, daiablility H-reflex, and Diffusion Tensor Imaging (DTI) Parameters in Patients With Lumbosacral Radiculopathy.
Detailed Description
Participants will receive Multimodal Physical Therapy program consisting of electrophysical agents, manual therapy interventions, and core stability exercises. Patients will receive the intervention for six weeks. Outcomes will be assessed at baseline and post-intervention.
Investigators
Mohamed Badr Hassanein
Mr
Cairo University
Eligibility Criteria
Inclusion Criteria
- •chronic (≥ 3 months) unilateral Lumbosacral Radiculopathy (LSR)
- •The LSR is due to paracentral L4-L5 or L5-S1 Lumbar disc herniation
- •The LSR is confirmed radiologically by MRI
- •The LSR is confirmed clinically by history and physical examination
- •The LSR is confirmed neurophysiological by soleus H-reflex assessment
- •Body mass Index less than 30
- •20-45 years of age
Exclusion Criteria
- •systematic disease
- •Bilateral symptoms
- •Lumbar spinal stenosis
- •previous surgery
- •Steroid injection
- •Spinal fracture
- •Lumbar spinal stenosis
- •Spinal deformity
- •Spinal fracture
- •Radiological evidence of bilateral nerve root encroachmen
Outcomes
Primary Outcomes
Disability
Time Frame: Change from Baseline Disability at 6 weaks
Roland-Morris Disability Questionnaire (RMDQ)
Apparent diffusion coefficient (ADC) of the compressed nerve root
Time Frame: Change from Baseline Apparent diffusion coefficient (ADC) at 6 weaks
by MRI examination
Fractional anisotropy (FA) of the compressed nerve root
Time Frame: Change from Baseline Fractional anisotropy (FA) ratio at 6 weaks
by MRI examination
Pain
Time Frame: Change from Baseline pain at 6 weaks
Visual analog scale (VAS)
Soleus H-reflex amplitude
Time Frame: Change from Baseline Soleus H-reflex amplitude at 6 weaks
by EMG unit
Soleus H-reflex side-to-side amplitude (H/H) ratio
Time Frame: Change from Baseline Soleus H/H ratio at 6 weaks
by EMG unit