Effects of Multimodal Physical Therapy on Pain, Disability, H-reflex, and Diffusion Tensor Imaging Parameters in Patients With Lumbosacral Radiculopathy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Disability
研究概览
简要总结
Purposes of the study
To investigate the effect of Multimodal Physical Therapy on pain, daiablility H-reflex, and Diffusion Tensor Imaging (DTI) Parameters in Patients With Lumbosacral Radiculopathy.
详细描述
Participants will receive Multimodal Physical Therapy program consisting of electrophysical agents, manual therapy interventions, and core stability exercises. Patients will receive the intervention for six weeks. Outcomes will be assessed at baseline and post-intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •chronic (≥ 3 months) unilateral Lumbosacral Radiculopathy (LSR)
- •The LSR is due to paracentral L4-L5 or L5-S1 Lumbar disc herniation
- •The LSR is confirmed radiologically by MRI
- •The LSR is confirmed clinically by history and physical examination
- •The LSR is confirmed neurophysiological by soleus H-reflex assessment
- •Body mass Index less than 30
- •20-45 years of age
排除标准
- •systematic disease
- •Bilateral symptoms
- •Lumbar spinal stenosis
- •previous surgery
- •Steroid injection
- •Spinal fracture
- •Lumbar spinal stenosis
- •Spinal deformity
- •Spinal fracture
- •Radiological evidence of bilateral nerve root encroachmen
- •Evidence of H-reflex amplitude or latency affection on asymptomatic side
结局指标
主要结局
Disability
时间窗: Change from Baseline Disability at 6 weaks
Roland-Morris Disability Questionnaire (RMDQ)
Apparent diffusion coefficient (ADC) of the compressed nerve root
时间窗: Change from Baseline Apparent diffusion coefficient (ADC) at 6 weaks
by MRI examination
Fractional anisotropy (FA) of the compressed nerve root
时间窗: Change from Baseline Fractional anisotropy (FA) ratio at 6 weaks
by MRI examination
Pain
时间窗: Change from Baseline pain at 6 weaks
Visual analog scale (VAS)
Soleus H-reflex amplitude
时间窗: Change from Baseline Soleus H-reflex amplitude at 6 weaks
by EMG unit
Soleus H-reflex side-to-side amplitude (H/H) ratio
时间窗: Change from Baseline Soleus H/H ratio at 6 weaks
by EMG unit
次要结局
未报告次要终点