positive end pressure ventilation effects on lungs during abdominal surgery

Completed

Conditions: Medical and Surgical,

Registration Number: CTRI/2023/11/059682

Lead Sponsor: DR SYED HAZARATH NABI

Brief Summary: PURPOSE OF THE STUDY:-

Patients undergoing mechanical ventilation during the surgery are prone to lung atelectasis postoperatively. application of appropriate levels of PEEP and using lung protective ventilation strategies not only reduces post operative atelectasis but also decreases post operative pulmonary complications like barotrauma, ateletrauma and acute lung injury. So, we intended to study the effects of different levels of PEEP application during intraoperative ventilation on the incidence of postoperative atelectasis.

in our study, we found that patients intervened with PEEP 4 or PEEP 8 did not have any postoperative atelectasis. but there was a significant hypotension, increased peak pressures, plateau pressures in the group B i.e., PEEP 8 than Group A PEEP 4.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 50

Inclusion Criteria

PATIENT OLDER THAN 18 YRS OF AGE AND UNDERGOING OPEN ABDOMINAL SURGERY OF EXPECTED DURATION MORE THAN 2 HOURS. PATIENTS WITH AMERICAN SOCIETY OF ANAESTHESIOLOGISTS(ASA) PHYSICAL STATUS 1.
3 AND BODY MASS INDEX LESS THAN 35Kg/meter2.

Exclusion Criteria

LAPAROSCOPIC SURGERIES PREVIOUS LUNG OR THORACIC SURGERIES PERSISTANT HAEMODYNAMIC INSTABILITY HISTORY OF COPD SYSTEMIC CORTICOSTERIOD THERAPY RECENT IMMUNOSUPPRESSIVE MEDICATION AND RADIOTHERAPY SEVERE CARDIAC DISEASE AS NYHA CLASS 3 -4 PREGNANCY ACUTE LUNG INJURY OR ARDS.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TO COMPARE THE EFFECT OF POSITIVE END EXPIRATORY PRESSURE UNDER GENERAL ANAESTHESIA FOR OPEN ABDOMINAL SURGERIES MORE THAN 2 HOURS OF DURATION ON POST OPERATIVE ATELECTASIS	LUNG ULTRASOUND IS PERFORMED IN PREOPERATIVE ROOM BEFORE SURGERY AND 30 MINUTES AFTER THE SURGERY

Secondary Outcome Measures

Name	Time	Method
TO DETERMINE THE DEGREE AND INCIDENCE OF HYPOTENSION DURING THE INTRAOPERATIVE MECHANICAL VENTILATION	TO DETERMINE THE INCIDENCE OF INCREASED AIRWAY PRESSURES AND BAROTRAUMA DURING INTRAOPERATIVE MECHANICAL VENTILATION

Trial Locations

Locations (1): R.L.JALAPPA HOSPITAL AND RESEARCH CENTRE
🇮🇳
Kolar, KARNATAKA, India
R.L.JALAPPA HOSPITAL AND RESEARCH CENTRE
🇮🇳Kolar, KARNATAKA, India
DR SYED HAZARATH NABI
Principal investigator
8553652356
hazarath.syed@outlook.com