EFFECT OF POSITVE END EXPIRATORY PRESSURE ON POST OPERATIVE ATELECTASIS FOR OPEN ABDOMINAL SURGERY : A PROSPECTIVE RANDOMIZED CONTROLLED STUDY
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- TO COMPARE THE EFFECT OF POSITIVE END EXPIRATORY PRESSURE UNDER GENERAL ANAESTHESIA FOR OPEN ABDOMINAL SURGERIES MORE THAN 2 HOURS OF DURATION ON POST OPERATIVE ATELECTASIS
研究概览
简要总结
PURPOSE OF THE STUDY:-
Patients undergoing mechanical ventilation during the surgery are prone to lung atelectasis postoperatively. application of appropriate levels of PEEP and using lung protective ventilation strategies not only reduces post operative atelectasis but also decreases post operative pulmonary complications like barotrauma, ateletrauma and acute lung injury. So, we intended to study the effects of different levels of PEEP application during intraoperative ventilation on the incidence of postoperative atelectasis.
in our study, we found that patients intervened with PEEP 4 or PEEP 8 did not have any postoperative atelectasis. but there was a significant hypotension, increased peak pressures, plateau pressures in the group B i.e., PEEP 8 than Group A PEEP 4.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •PATIENT OLDER THAN 18 YRS OF AGE AND UNDERGOING OPEN ABDOMINAL SURGERY OF EXPECTED DURATION MORE THAN 2 HOURS. PATIENTS WITH AMERICAN SOCIETY OF ANAESTHESIOLOGISTS(ASA) PHYSICAL STATUS
- •3 AND BODY MASS INDEX LESS THAN 35Kg/meter2.
排除标准
- •LAPAROSCOPIC SURGERIES PREVIOUS LUNG OR THORACIC SURGERIES PERSISTANT HAEMODYNAMIC INSTABILITY HISTORY OF COPD SYSTEMIC CORTICOSTERIOD THERAPY RECENT IMMUNOSUPPRESSIVE MEDICATION AND RADIOTHERAPY SEVERE CARDIAC DISEASE AS NYHA CLASS 3 -4 PREGNANCY ACUTE LUNG INJURY OR ARDS.
结局指标
主要结局
TO COMPARE THE EFFECT OF POSITIVE END EXPIRATORY PRESSURE UNDER GENERAL ANAESTHESIA FOR OPEN ABDOMINAL SURGERIES MORE THAN 2 HOURS OF DURATION ON POST OPERATIVE ATELECTASIS
时间窗: LUNG ULTRASOUND IS PERFORMED IN PREOPERATIVE ROOM BEFORE SURGERY AND 30 MINUTES AFTER THE SURGERY
次要结局
- TO DETERMINE THE DEGREE AND INCIDENCE OF HYPOTENSION DURING THE INTRAOPERATIVE MECHANICAL VENTILATION(TO DETERMINE THE INCIDENCE OF INCREASED AIRWAY PRESSURES AND BAROTRAUMA DURING INTRAOPERATIVE MECHANICAL VENTILATION)