Pathogenic microbes: an exploration for their driving role in colitis associated cancer
Recruiting
- Conditions
- colitis associated cancercolon cancer1001796910017991
- Registration Number
- NL-OMON43486
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
For ulcerative colitis (N<=80):
* Left-sided colitis or pancolitis (Montreal score E2 or E3)
* > 8 years of disease duration
* At time of colonoscopic surveillance in clinical remission (Montreal score S0);For controls (N<=40):
* Routine scheduled colonoscopy for iron deficiency anemia, changed stool pattern, irritable bowel syndrome or status post-diverticulitis
* no abnormal findings during colonoscopy
Exclusion Criteria
Exclusion criteria for UC-patients and controls:
* Oral antibiotics in last 3 months before colonoscopy (drastically affects the mucosal microbiota);Exclusion criteria for controls only:
* No history of CRC and UC or other inflammatory disease of the intestine
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method