CTRI/2024/06/069040尚未招募3 期
Prospective randomized study to evaluate the impact of radiotherapy and radiotherapy technique on neurocognitive profile in grade 2 and 3 gliomas. - NI
Post Graduate Institute of Medical Education and Research PGIMER Chandigarh0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Patients with infiltrative lower grade gliomas (grade 2-3) who have undergone tumor removal or at least biopsy with histopathologic confirmation.
- •2.Cranial radiotherapy is clinically indicated to prevent recurrence due to presence of high risk features (astrocytoma histology), subtotal resection (STR) or age older than 40 years.
- •3.Karnofsky Performance Status Scale score (KPS)
- •more than or equal to 60.
- •4.No prior history of radiation to the brain.
- •5.No contraindications to contrast enhanced computed tomography (CECT) and contrast enhanced magnetic resonance imaging (CEMRI).
- •6.Routine blood parameters (Complete blood count (CBC), liver function test (LFT), kidney function test (KFT)) within normal limits.
- •7.Willing to give consent for the study.
排除标准
- •1)Any non malignant known CNS disease that can cause neurocognitive dysfunction.
- •2)Pregnant and lactating women.
- •3)Prior long term chemotherapy.
- •4)Moderate or severe neurocognitive dysfunction prior to radiotherapy (MMSE less than or equal to 18)
研究者
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