The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture
Terminated
- Conditions
- Breast Cancer
- Registration Number
- NCT00481585
- Lead Sponsor
- Hackensack Meridian Health
- Brief Summary
The objective of the present study is to determine whether or not primary human mammary epithelial cells are competent for use in molecular studies of transepithelial electrophysiology focusing on the function of the tight junction protein claudin 3.
Human breast Tissue will be removed from mastectomy specimens and used as a source to generate epithelial cells for study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Female
- Target Recruitment
- 13
Inclusion Criteria
- Subjects of this pilot study are limited to those female patients who are undergoing therapeutic or prophylactic mastectomy procedures conducted by the department of Surgery at HUMC.
Exclusion Criteria
- From within this population, no exclusion criteria shall be applied based on age, race, ethnicity, gender, HIV status, or menopause.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cell line data study one year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hackensack Univeristy Medical Center
🇺🇸Hackensack, New Jersey, United States