COMPARATIVE EVALUATION OF CRYOTHERAPY AND SILVER NP–CHITOSAN NP IRRIGATION REGIMEN TO STANDARD IRRIGATION REGIMEN IN POST-OPERATIVE PAIN REDUCTION IN THE INDIVIDUALS NEEDING ENDODONTIC TREATMENT : A RANDOMISED DOUBLE-BLINDED CLINICAL TRIAL.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Post-operative pain on Visual Analogue Scale (VAS)
研究概览
简要总结
Aim - To compare and evaluate the post operative pain reduction in cryotherapy and/or Silver NP – Chitosan NP nanoparticle irrigation regimen with the standard irrigation regimen in individuals needing endodontic treatment.
Objectives -
-
Compare and evaluate post operative pain after endodontic treatment done with standard irrigation regimen at cryotherapy temperatures and room temperature.
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Compare and evaluate post operative pain after endodontic treatment done with Silver NP – Chitosan NP nanoparticle irrigation regimen at cryotherapy temperatures and room temperature.
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Compare and evaluate post operative pain after endodontic treatment done with Silver NP – Chitosan NP nanoparticle irrigation regimen and standard irrigation regimen, at room temperature.
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Compare and evaluate post operative pain after endodontic treatment done with Silver NP – Chitosan NP nanoparticle irrigation regimen and standard irrigation regimen, at cryotherapy temperature.
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Compare anti-microbial effectiveness of Silver NP – Chitosan NP nanoparticle irrigation regimen with standard irrigation regimen in infected teeth requiring endodontic treatment.
Hypothesis -
There is a difference in post-operative pain reduction between individuals receiving endodontic treatment with cryotherapy and/or Silver NP – Chitosan NP nanoparticle irrigation regimen & standard irrigation regimen.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Mature, Permanent Premolar or Molar Teeth requiring endodontic treatment.
- •Pulpal and Periapical Diagnoses –
- •Symptomatic irreversible pulpitis (SIP);
- •Symptomatic irreversible pulpitis (SIP) with Symptomatic Apical Periodontitis (SAP);
- •Symptomatic Apical Periodontitis (SAP) without Symptomatic irreversible pulpitis (SIP);
- •Pulpal Necrosis (PN) with Symptomatic Apical Periodontitis (SAP).
排除标准
- •Morbid Individuals with Systemic Diseases.
- •Individuals in gestational or lactation period.
- •Aberrant root canal anatomies.
- •Pulp Space Calcifications.
- •Badly Broken-down teeth.
- •Secondary endodontic infection
- •Periodontally compromised teeth.
- •Rubber dam isolation not possible.
结局指标
主要结局
Post-operative pain on Visual Analogue Scale (VAS)
时间窗: Immediate Post-Op, at 6 hours, 12 hours, 24 hours, 72 hours and 1 week.
次要结局
- post operative pain(one week postoperatively)
研究者
Dr Sarathi Vin
T.P.C.Ts Terna Dental College and Hospital