Impact of Positive & Negative Lens-Induced Defocus on Contrast-Sensitivity in Myopic & Non-Myopic Adults

Not Applicable

Active, not recruiting

• Conditions: Myopia

• Registration Number: NCT06753032
• Lead Sponsor: Superior University

Brief Summary

examines the influence of lens-induced defocus on contrast sensitivity-a crucial aspect of visual performance.Each participant experiences both positive and negative defocus through different lenses, with measurements taken for contrast sensitivity using the Pelli-Robson chart. Outcomes are evaluated at baseline, 2 weeks, and 4 weeks to understand the effect of defocus over time.

Detailed Description

Additional data on symptoms like visual fatigue and computer vision syndrome are gathered using the Visual Fatigue Questionnaire (VFQ) and the Computer Vision Syndrome Questionnaire (CVS-Q), respectively. This study's findings could be instrumental in refining optical treatments, offering insights into how defocus impacts visual function across refractive conditions. Results may ultimately benefit optometric practices by guiding lens prescriptions for improved contrast sensitivity and quality of life for myopic and non-myopic individuals alike.

Study Timeline

• Study Start: 2024-02-28
• Primary Completion: 2024-07-31
• Status Verified: 2024-12
• Study First Submitted: 2024-12-13
• Study First Submitted QC: 2024-12-22
• Last Update Submitted: 2024-12-22
• Study First Posted: 2024-12-31
• Last Update Posted: 2024-12-31
• Study Completion: 2025-03-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Adults aged 18 to 50 years.
• Participants with a confirmed diagnosis of myopia or non-myopia.
• Best corrected visual acuity of 20/30 or better.
• No history of ocular surgery or significant ocular disease.
• Informed consent was obtained.

Exclusion Criteria

• Individuals with a history of systemic diseases affecting vision (e.g., diabetes, hypertension).
• Presence of binocular vision anomalies or strabismus.
• Pregnant or nursing women.
• Any current use of medications affecting visual function (e.g., medications causing visual side effects).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Contrast Sensitivity	12 Months	Measured with the Pelli-Robson Contrast Sensitivity Chart, capturing changes in participants' ability to detect low-contrast visual stimuli under defocus conditions.
Visual Fatigue	12 months	Evaluated with the Visual Fatigue Questionnaire (VFQ) and Computer Vision Syndrome assessing symptoms like eye strain, discomfort, and fatigue following lens-induced defocus.

Trial Locations

Locations (1)

Tehsil Headquarters (THQ); 🇵🇰 Taunsa, Punjab, Pakistan