Transdermal Testosterone for Poor Responder Patients Undergoing Controlled Ovarian Stimulation Prior to IVF
- Registration Number
- NCT03078569
- Lead Sponsor
- Wolfson Medical Center
- Brief Summary
This study evaluates the efficacy of pre- IVF treatment with transdermal testosterone to enhance ovarian response in poor responders.
a randomized controlled trial with two groups, treatment group with transdermal testosterone before IVF treatment and a control group with no treatment.
- Detailed Description
One of the major challenges of Assisted reproduction technology is treating women with low ovarian response,those women achieve very poor pregnancy rate with IVF.
in recent years there is a focus
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 30
Inclusion Criteria
- infertility patients undergoing ART regular menses normal function of thyroid, liver and kidney normal BMI (19.3-28.9) without use of any fertility drugs in the previous two months
Exclusion Criteria
- patients with recurrent implantations failure (3 cycles and more) previous ovarian surgery uncontrolled medical illness severe endometriosis (stage 3-4) contraindication for testosterone use
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description testosterone gel Testosterone gel testosterone gel treatment group
- Primary Outcome Measures
Name Time Method number of retrieved oocytes 2 year number of oocytes
- Secondary Outcome Measures
Name Time Method number of clinical pregnancies 2.5 years number of pregnancies with fetal cardiac activity
Trial Locations
- Locations (1)
Wolfson MC
🇮🇱Holon, Israel