Meniscus Transplantation in Symptomatic Patients Under Fifty Years of Age: Survivorship Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 76
- 主要终点
- Survivorship analysis
研究概览
简要总结
The purpose of this study is to determine the long-term survivorship and clinical outcomes of all cryopreserved meniscus transplants performed by Dr. Frank Noyes.
详细描述
All patients receiving cryopreserved meniscus transplants will be followed at 1, 2, 5, 10, and 15 years postoperatively. Study examination will include comprehensive knee examination by Dr. Noyes, x-rays, and potentially MRI. Patients will complete the following forms of the Cincinnati Knee Rating System: Symptom Rating Form, Sports Activity and Function Form, and Occupational Rating Form. All patient identification will be kept confidential. Patient data will be entered into the Knee Registry database according to their unique study number by the clinical research assistant.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 14 Years 至 49 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient post-meniscectomy
- •Patient symptomatic with activities
- •Patient has early articular cartilage degeneration in affected tibiofemoral compartment
- •Patient understands goals of operation, willing to undergo lengthy rehabilitation
排除标准
- •Patient has no symptoms with activities
- •Patient has advanced degeneration in affected tibiofemoral compartment or other compartments
- •Patient is obese (BMI > 30)
- •Patient has uncorrected lower limb axial malalignment or knee ligament deficiency
- •Patient has active infection
- •Patient has pre-existing knee arthrofibrosis or lower limb muscular atrophy
- •Patient has symptomatic patellofemoral articular cartilage deterioration
- •Patient is unwilling to undergo lengthy rehabilitation after surgery
结局指标
主要结局
Survivorship analysis
时间窗: 15 years postoperatively
次要结局
- International Knee Documentations Committee(15 years postoperatively)
- Cincinnati Knee Rating System(15 years postoperatively)