Aging With Pride: Innovations in Dementia Empowerment and Action
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 322
- 试验地点
- 1
- 主要终点
- Change in Physical Activity of Care Recipient
研究概览
简要总结
The lack of efficacious research-based interventions for such vulnerable older adults with Alzheimer's disease and related dementias (AD/RD) and their caregivers (CGs) is a significant public health problem. Caregiving of sexual/gender minority older adults with AD/RD is of concern due to social stigma, marginalization, and isolation, which may be barriers to sustaining caregiving. It is necessary and timely to translate evidence-based culturally adaptable interventions for this underserved and stigmatized population. Reducing Disability in Alzheimer's Disease (RDAD) has been evaluated in a randomized controlled trial and has shown to successfully train community-dwelling CR (care receiver)-CG dyads to increase the physical activity and functioning of individuals with AD/RD and their CGs and to teach CGs techniques for managing behavioral symptoms of CRs. RDAD consequently decreases stress of CGs, delays institutionalization of CRs, and increases health related quality of life (HRQOL) of CRs and CGs. Thus, this study will evaluate the effect of the standard RDAD among lesbian, gay, bisexual, and transgender (LGBT) CRs with AD/RD and their CGs, and this study will test a personalized intervention tailored to better respond to distinct risks experienced by CGs and LGBT CRs with AD/RD, addressing unique sexual/gender minority CG risk factors (e.g., identity management, stigma-related adverse or traumatic life events, and lack of social support).
详细描述
We will address the following aims:
Aim 1. Test the translation and enhancement of intervention designed to increase physical activities of older adult care receivers (CRs) with AD/RD and their CGs. Aim 2. Evaluate the short- and long-term effect of the standard and personalized intervention on primary (physical activity and functioning; perceived stress for CGs; independence/residential status (institutionalization) for CRs) and secondary outcomes (HRQOL; depressive symptomatology; behavioral disturbances for CRs). Aim 3. Test the moderating roles of CR-CG characteristics, including type of CR-CG relationship, sex, and severity of CR AD/RD, on the treatment effect of the standard and personalized intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
Participants receiving intervention will not be informed whether it is the standard or personalized treatment.
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •for care receiver
- •Age at enrollment is 50 years of age or older
- •Have dementia, (e.g., Alzheimer's disease, mild cognitive impairment, Vascular dementia, Parkinson's disease, Lewy Body dementia) or memory loss significant enough to affect daily activities
- •Living in the community, not in a care facility.
- •Living in the U.S.
- •Either the care receiver or care giver must self-identify as LGBT (or sexual or gender non-binary or same sex sexual behavior)
- •Inclusion criteria for care giver
- •Provide care to the care recipient with dementia.
- •Willing to spend 30 minutes daily for study activities (or coordinate for someone to.)
- •Live in the community, not in a care facility
- •Living in the U.S.
- •Neither care receiver nor caregiver:
- •Has known terminal illness (with death anticipated within the next 12 months)
- •Was hospitalized for a psychiatric disorder in the 12 months prior to baseline
- •Is currently suicidal or having major hallucinations or delusions
- •Plans to move to long term care setting within 6 months of enrollment.
- •Has any physical limitations/chronic conditions preventing participation in an exercise program.
排除标准
- 未提供
研究组 & 干预措施
Standard intervention
Reducing Disabilities in Alzheimer's Disease (RDAD):
9 60-minute virtual sessions for 6 weeks and 4 15-minute follow-up phone sessions for 4 months
干预措施: Reducing Disabilities in Alzheimer's Disease (RDAD) (Behavioral)
Personalized intervention
Innovations in Dementia Empowerment and Action (IDEA):
9 60-minute virtual sessions for 6 weeks and 4 15-minute follow-up phone sessions for 4 months
干预措施: Innovations in Dementia Empowerment and Action (IDEA) (Behavioral)
结局指标
主要结局
Change in Physical Activity of Care Recipient
时间窗: Baseline, 6 weeks(pre-treatment), 13 weeks(post-treatment), 30 weeks, 13 months
Measured by the days of aerobic activity for at least 30 minutes in the past week with higher numbers indicating more days of activity.
次要结局
- Memory-Related Disturbance, Care Recipient(Baseline, 6 weeks(pre-treatment), 13 weeks(post-treatment), 30 weeks, 13 months)
- Depression of Care Partner: Center for Epidemiological Studies-Depression Scale (CESD-10)(Baseline, 6 weeks(pre-treatment), 13 weeks(post-treatment), 30 weeks, 13 months)
- Quality of Life in Alzheimer's Disease, Care Recipient(Baseline, 6 weeks(pre-treatment), 13 weeks(post-treatment), 30 weeks, 13 months)
- Perceived Stress of Care Partner(Baseline, 6 weeks (Pre-treatment), 13 weeks (Post-treatment), 30 weeks, 13 months)
- Physical Functioning of Care Recipient: Medical Outcomes Study 36-Item Short Form (SF-36)(Baseline, 6 weeks(pre-treatment), 13 weeks(post-treatment), 30 weeks, 13 months)
研究者
Karen Fredriksen Goldsen
Professor
University of Washington