Diaphragmatic Breathing Exercises in Total Knee Arthroplasty Patients

Recruiting

• Conditions: Anesthesia and Analgesia
• Interventions: Behavioral: Diaphragmatic Breathing

• Registration Number: NCT04336579
• Lead Sponsor: University of Southern California

Brief Summary

Rationale: While total knee replacements (TKA) are one of the most commonly performed surgical procedures in the United States, this procedure can also be very painful. Postoperative mobilization and rehabilitation is vital to a patient's recovery, but inadequate pain control can impede patients' progress. Diaphragmatic breathing is an additional non-pharmacological and non-invasive tool with no adverse effects that could aid in recovery. This will serve as a pilot study for a possible larger controlled trials.

Detailed Description

Study population: Patients (participants) undergoing total knee arthroplasty at Keck USC Hospital at HC3

Study methodology: Patients (participants) will be taught with the aide of a handout and instructional videos preoperatively and in the recovery room on how to perform diaphragmatic breathing exercises for post-operative pain control. Patient (participant) pain levels will be assessed using the visual analog scale (VAS). The investigators will then be comparing VAS scores and daily opioid doses (morphine equivalents) between the study group and a control group. The control group will include prior patients (participants) over the past year who underwent TKA at Keck Hospital and also had pain scores and opioid usage measured, but did not receive the breathing treatment.

Study endpoints: Endpoints will include: pain levels via VAS scale, anxiety levels via VAS scale, and opioid usage (morphine equivalents).

Study Timeline

• Study First Submitted: 2019-12-19
• Study First Submitted QC: 2020-04-02
• Study First Posted: 2020-04-07
• Study Start: 2024-06-10
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-25
• Last Update Posted: 2024-08-27
• Primary Completion: 2024-10-01
• Study Completion: 2024-10-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Patients (participants) undergoing total knee arthroplasty with a continuous peripheral nerve block catheter

Exclusion Criteria

• Inability to perform or learn diaphragmatic breathing exercises or do not wish to participate in diaphragmatic breathing or study protocol
• Pregnant patients
• Patients without continuous peripheral nerve block catheter

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Diaphragmatic Breathing	Diaphragmatic Breathing	Intervention: Participants will perform diaphragmatic breathing exercises postoperatively as part of their multi-modal pain regimen.

Primary Outcome Measures

Name	Time	Method
Opioid Usage (morphine equivalents)	1 day after intervention	Opioid Usage for pain
Anxiety Level	1 day after intervention	Verbal Analog Score - rate anxiety on 0-10 scale where 0 = no anxiety, 10 = worst possible pain
Pain Level	1 day after intervention	Verbal Analog Pain Score - rate pain on 0-10 scale where 0 =no pain, 10 = worst possible pain

Trial Locations

Locations (1)

Keck Hospital of USC; 🇺🇸 Los Angeles, California, United States