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Home Pulse Oximeter Use in Patients With COVID-19

Not Applicable
Completed
Conditions
Sars-CoV2
COVID-19
COVID
Registration Number
NCT04373161
Lead Sponsor
Swedish Hospital
Brief Summary

The purpose of this study is to investigate the use of home pulse oximetry monitoring in patients with COVID-19 to trend disease progression and identify need for hospitalization.

Detailed Description

This protocol studies patients with suspected non-severe Corona Virus Disease (COVID-19) being discharged to home from an emergency department (ED) or outpatient testing center. Patients will be provided a portable fingertip home pulse oximeter that measures peripheral oxygen saturation (SpO2). Patients will be instructed to check their resting home oxygen saturation three times per day and record these findings. They will be instructed to return to the emergency room for sustained oxygen saturation below 92% or if their symptoms are worsening and they feel they need medical attention. Patients will be called once daily by the research team to collect data in real time. Patients will be monitored for seven days, and at the end of the seven day period, they will return the pulse oximeter as well as a spreadsheet of their home oximetry readings. The purpose is to see if home pulse oximetry identifies disease progression and need for hospitalization in patients with COVID-19. Additionally, there will be analysis of trends in home oximetry readings wand predictors of morbidity and mortality.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
209
Inclusion Criteria
  • Patients with suspected COVID-19 as defined by the World Health Organization
  • Age > 18
Exclusion Criteria
  • Pregnancy
  • Prisoners
  • Lack of decision making capacity or cannot provide consent
  • Patients being admitted to the hospital
  • Patients on home oxygen
  • Patients being discharged to a skilled nursing facility

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Hospitalization in COVID-19 patients with low home SpO27 days after enrollment

The primary outcome is the relative risk of hospitalization in COVID-19 patients with resting home pulse oximeter SpO2 below 92%.

Secondary Outcome Measures
NameTimeMethod
Trend in resting home pulse oximetry readings7 days after enrollment

The purpose of this outcome is to determine if home pulse oximetry readings abruptly drop, gradually decline, or stay level in patients with COVID-19

Timing of SpO2 <92%7 days after enrollment

This will evaluate if there is a correlation between the time of day with SpO2 readings below 92 percent in patients with suspected COVID-19.

Home pulse oximeter use effect on subsequent ED visits7 days after enrollment

The goal of this outcome is to see if patients enrolled in the study are reassured by use of home pulse oximeter monitoring and if this device prevents subsequent ED visits by patients

Reason for return to the Emergency Department7 days after enrollment

To see if patients who return to the ED and end up hospitalized did so for incidental finding of low home pulse oximetry or if it was for worsening symptoms

Hospitalization outcome - morbidityUp to 21 days after enrollment

The study will assess development of morbidity defined as intensive care unit admission, acute respiratory distress syndrome, and/or septic shock in patients with SpO2 \<92%

Hospitalization outcome - mortalityUp to 21 days after enrollment

The study will assess mortality defined as death after admission to the hospital in patients with SpO2 \<92%

Median Length of StayUp to 21 days after enrollment

The study will measure median length of stay in patients with COVID-19 that are hospitalized on subsequent return to the ED.

Trial Locations

Locations (1)

Swedish Hospital

🇺🇸

Chicago, Illinois, United States

Swedish Hospital
🇺🇸Chicago, Illinois, United States

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