Internal Jugular Vein Sonogram Versus Electrical Cardiometry For Assessment Of Fluid Responsiveness In Adult Undergoing Coronary Artery Bypass Graft Surgery
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- fluid responsiveness after fluid challenge
Study Overview
Brief Summary
The primary aim of the study is to assess the reliability of predicting fluid responsiveness in adults undergoing coronary artery bypass graft surgery using sonogram of the internal jugular vein for assessment of vessel distensibility in relation to stroke volume variation (SVV) measaured by electrical cardiometry.
The secondary aim is to evaluate the ability of thoracic fluid content (TFC) measured by electrical cardiometry to be an additive value for the assessment of fluid responsiveness.
Detailed Description
Fluid management is one of the most important treatments for stabilizing hemodynamics in patients after cardiac surgery.Electrical Cardiometry is a method for the non-invasive determination of stroke volume (SV), cardiac output (CO), stroke volume variation (SVV) and other hemodynamic parameters in adults, children, and neonates based on measurement of thoracic electrical bioimpedance and has been validated against "gold standard" methods such as thermodilution method of deriving CO using a pulmonary artery catheter (PAC).
The IJV is, technically, much more easily accessible for sonographic visualization than the IVC, and measurement of the IJV does not require transesophageal echocardiography (TEE). Internal jugular vein distensibility index (IJVDI) has been studied in several studies but its reliability has not been well confirmed in patients during cardiac surgery.
This is a prospective observational study of adults undergoing coronary artery bypass graft surgery . The primary aim of the study is to assess the reliability of predicting fluid responsiveness in adults undergoing coronary artery bypass graft surgery using sonogram of the internal jugular vein for assessment of vessel distensibility in relation to stroke volume variation (SVV) measaured by electrical cardiometry.The secondary aim is to evaluate the ability of thoracic fluid content (TFC) measured by electrical cardiometry to be an additive value for the assessment of fluid responsiveness.
Volume responsiveness will be independently assessed by IJV sonogram and electrical cardiometry in following times
- After induction of anesthesia.
- After transfusing 6 ml / kg of hydroxyethyl starch (HES) 6% before sternotomy.
- After closure of the sternum and transfusion of patient's blood.
- Immediately before transferring the patient to ICU and stabilization of hemodynamic parameters by giving fluids needed to patient.
- Immediately after transferring the patient to ICU and stabilization of hemodynamic parameters by giving fluids needed to patient.
- After 2 hour of ICU admission.
- Before weaning from mechanical ventilation Fluid responsiveness will be assessed by examining SVV with a threshold of the SVV = 12% allow discrimination between Responders and Non-responders
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adults (>18 years old) Able to provide advanced informed consent Planned for elective CABG surgery
Exclusion Criteria
- •Age < 18 years
- •Severely reduced preoperative left ventricular ejection fraction < 40 %
- •Significant cardiac arrhythmia.
- •Significant valvular heart disease.
- •Clinically evident pulmonary disease.
- •Bilaterally inserted venous catheters (jugular or subclavian vein)
- •History of radiotherapy or surgery of the neck region.
- •Inability to obtain interpretable ultrasound images due to a difficult acoustic window.
Outcomes
Primary Outcomes
fluid responsiveness after fluid challenge
Time Frame: 24 hours from the start of surgery
Correlation between SVV and IJVDI
Secondary Outcomes
No secondary outcomes reported
Investigators
Ahmed Abd El-Rahim Abd El-Hamid Hammad
Residentat department of anaesthesia and surgical intensive Care
Alexandria University