The Effects Assessment of the Polygonatum Kingianum Extract on Endurance Performance and Anti-fatigue
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The change of blood PDE5 gene expression
研究概览
简要总结
To assess the efficacy of polygonatum kingianum extract on endurance performance and anti-fatigue
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy male aged 30-60 years old
- •Must read and sign the informed consent form
- •During the experiment, do not change the lifestyle and eating habits
- •Cooperate not to engage in high-intensity exercise 48 hours before each experiment
排除标准
- •Subject who is not willing to participate in this study.
- •People with serious diseases of heart, liver, kidney, endocrine and other organs (such as hypertension, diabetes, renal dysfunction and heart-related diseases) and mental patients
- •People who have undergone surgery within 6 months or have lower limb injuries
- •People who are allergic to Polygonatum kingianum extract
- •Participate in other clinical trials related to anti-fatigue within four weeks of the trial
- •Students who are currently taking courses taught by the principal investigator of this trial.
研究组 & 干预措施
Placebo drink
consume 1 bottle per day
干预措施: Placebo drink (Dietary Supplement)
Polygonatum kingianum extract drink
consume 1 bottle per day
干预措施: Polygonatum kingianum extract drink (Dietary Supplement)
结局指标
主要结局
The change of blood PDE5 gene expression
时间窗: Day 0, day 14, day28
Fasting venous blood was sampled to measure the expression of PDE5 gene
The change of aerobic endurance
时间窗: Day 0, day 14, day28
3-min step test is used to assess aerobic endurance
The change of continuous attention performance
时间窗: Day 0, day 14, day28
Canon continuous attention software (Conners' Continuous Performance Test) is used to assess continuous attention performance
The change of concentration of testosterone in blood
时间窗: Day 0, day 14, day28
Fasting venous blood was sampled to measure concentrations of testosterone
次要结局
- The change of blood nitric oxide (NO)(Day 0, day 14, day28)
- The change of self-assessment fatigue condition(Day 0, day 14, day28)