Comparison of dexmedetomidine for sedation and anxiolysis given by nasal and venous route in laparoscopic surgeries
Phase 3
- Conditions
- Health Condition 1: K811- Chronic cholecystitis
- Registration Number
- CTRI/2021/03/032009
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA I and II (American Society of Anaesthesiologists) scheduled for elective laparoscopic surgery were included in the study.
Exclusion Criteria
. Exclusion criteria included pregnancy, patients with ejection fraction <40%, age >60 years ,BMI >30kg/m2, valvular dysfunction , patients taking clonidine or α-methyldopa, patients with insulin dependent diabetes, renal or hepatic dysfunction patients with respiratory disorder, patients with history of CABG and patients in which intubation time was more than 20 seconds
Study & Design
- Study Type
- PMS
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)To compare and evaluate the efficacy of intranasal and intravenous dexmedetomidine as premedication before general anaesthesiaTimepoint: outcome will be assessed as baseline,t5,t10,t15,t20,t25,t30,t35,t40 where t is the time from intranasal administeration of drug/placebo
- Secondary Outcome Measures
Name Time Method To compare and evaluate sideeffects with intranasal and intravenous dexmedetomidine as premedicationTimepoint: side effects will be monitored and recorded at t5,t10,t15,t20,t25,t30,t35,t40 from administeration of intranasal study drug/placebo