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Phase II clinical trial of combination of personalized peptide vaccination and Juzen-taiho-to for Pancreatic cancer patients who failed standard therapy or unresectable.

Phase 2
Conditions
Pancreatic cancer
Registration Number
JPRN-UMIN000006295
Lead Sponsor
Kurume University Cancer Vaccine Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

The following patients must be excluded: 1) Patients with severe symptoms (active and severe infectious disease, circulatory disease, respiratory disease, kidney disease, immunodeficiency, disturbance of coagulation). 2)Active double cancer (synchronous double cancer and metachronous double cancer within 5 disease-free years), excluding carcinoma in situ (lesions equal to intraepithelial or intramucosal cancer) judged to have been cured with local treatment. 3) Patients with the past history of severe allergic reactions. 4) (Females) Patients who are during pregnancy, lactation expectant, and desiring future fertility. (Males) Patients do not accept contraception during the 1st vaccination to 70 days after the last vaccination. 5) Patients who are judged inappropriate for the clinical trial by doctors.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Comparison between two groups of immune-enhancing effects.
Secondary Outcome Measures
NameTimeMethod
1. Comparison between two groups of long-term prognosis. 2. Comparison between two groups of adverse,safety of peptide vaccination
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