The effect of a multispecies probiotic on the reconstruction of the intestinal microbiome after a colonoscopy
Recruiting
- Conditions
- Reconstruction of a reduced intestinal microbiome after a colonoscopy
- Registration Number
- DRKS00018115
- Lead Sponsor
- Institut Allergosan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Healthy volunteers (no diagnosed bowel disease)
Age 50-80 years
Consent to participate
Exclusion Criteria
Diagnosed, currently clinically relevant disease of the intestine
Taking other probiotics
Antibiotic therapy in the last 4 weeks
Lack of consent to participate in the study
Immunosuppressive therapy
Age <50 years and> 80 years
Taking proton pump inhibitors
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint is the reconstruction of the microbiome immediately after 30 days of intervention, which is analyzed by 16S rRNA microbiome analysis from stool samples.<br>OMNi-BiOTiC® Colonize is used for the management of a reduced intestinal microbiome after a colonoscopy, which was carried out as part of a preventive examination.
- Secondary Outcome Measures
Name Time Method Abdominal discomfort, Abnormalities of bowel movements (determined by Bristol Stool Scale)