A glucose lowering drug named Metformin is either continued or stopped on the morning of surgery and the blood glucose and serum lactate levels are measured.
Phase 4
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: E119- Type 2 diabetes mellitus without complications
- Registration Number
- CTRI/2022/10/046706
- Lead Sponsor
- D Ragha Renuka
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Diabetes Mellitus for more than 6 months duration using Metformin as a single agent, ASA II TO III, Serum creatinine levels < 1.6, posted for minor surgical procedures( both general and regional anaesthesia)
Exclusion Criteria
HbA1c >8%, patients with chronic or acute renal insufficiency, patients on insulin therapy, patients with liver insufficiency, patients using corticosteroids.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study and compare changes in blood glucose levels and serum lactate levels at different <br/ ><br>time intervals in diabetic patients undergoing elective minor surgeries under general or regional <br/ ><br>anaesthesia, with or without continuation of morning dose of metformin.Timepoint: Baseline, 1 hour after incision, 2 hours postoperative and 24 hours postoperative values
- Secondary Outcome Measures
Name Time Method To compare effect of continuing metformin in diabetic patients undergoing minor surgery <br/ ><br>on perioperative blood glucose in patients receiving general anaesthesia versus regional <br/ ><br>anaesthesia. <br/ ><br>2) To compare effect of continuing Metformin in diabetic patients undergoing minor surgery <br/ ><br>on perioperative lactate levels in patients receiving general anaesthesia versus regional <br/ ><br>anaesthesia. <br/ ><br>3) To study the requirement and amount of intraoperative insulin if any.Timepoint: Baseline, 1 hour after incision, 2 hours postoperative and 24 hours postoperative values