Prediction Model of Occult Omental Metastasis in Patients With Gastric Cancer

Recruiting

• Conditions: Gastric Cancer; Omental Metastasis

• Registration Number: NCT06405009
• Lead Sponsor: Northern Jiangsu People's Hospital

Brief Summary

A complete omentectomy is typically recommended during radical total gastrectomy for gastric cancer, though its impact on survival remains unclear. This study aimed to assess the frequency and risk factors of metastases in the greater omentum in gastric cancer patients undergoing gastrectomy. It will involve a single prospective cohort of consecutive patients who underwent total gastrectomy with complete en bloc omentectomy and modified D2 lymphadenectomy. Post-surgery, the omentum will dissect from the gastrectomy specimen beyond the gastroepiploic vessels and examine separately for pathological assessment. The primary outcome will focus on the detection of omental metastases.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-22
• Study First Submitted: 2024-04-22
• Status Verified: 2024-05
• Study First Submitted QC: 2024-05-05
• Last Update Submitted: 2024-05-05
• Study First Posted: 2024-05-08
• Last Update Posted: 2024-05-08
• Primary Completion: 2024-06-30
• Study Completion: 2024-06-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 450

Inclusion Criteria

1. pathological confirmation of gastric cancer
2. eligibility for surgical intervention
3. undergoing first rectal cancer surgery
4. acquisition of written informed consent from patients and their families
5. no history of hypertrophic scar or allergic predispositions

Exclusion Criteria

1. absence of postoperative pathology of the omentum
2. diagnosis of multiple primary malignancies
3. intraoperative discovery of widespread implant metastases within the abdominal cavity
4. severe comorbidities

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
patients with omental metastases	up to 2 weeks after gastric cancer surgery	After the operation, the postoperative pathological examination of the patient indicated the presence of omental metastases
patients without omental metastases	up to 2 weeks after gastric cancer surgery	After surgery, pathological examination confirmed no omental metastases

Trial Locations

Locations (1)

Yifan Cheng; 🇨🇳 Yangzhou, Jiangsu, China