Feasibiblity of treatment with heat in combination with intravescial chemotherapy in the treatment of non-muscle invasive bladder cancer.
Completed
- Conditions
- intermediate risk/high risk non-muscle invasive bladder carcinomaintermediate/hoge risico niet-spier invasief blaascarcinoom
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
1. Patients with an intermediate or high risk non-muscle invasive transitional cell carcinoma of the bladder according to the EAU definition; Ta-1 grade 3 or Ta-1 grade 2 recurrent or Carcinoma in situ;
2. A complete transurethral resection has to be performed within 3-6 weeks prior to study treatment. Complete tumour eradication must be verified by taking biopsies from suspected areas. The treatment session should begin 3-8 weeks after the initial TURB;
Exclusion Criteria
1. Intravesical MMC during the last 12 months;
2. Bladder tumors other than transitional cel carcinoma;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feasibility en toxicity.
- Secondary Outcome Measures
Name Time Method To develop a new bladder catheter with sufficient thermocouples to measure accurately the temperature on the bladder wall.<br>