Study protocol for a randomized clinical trial of a continuous butylscopolamine infusion versus a placebo in patients with a renal colic not responding to oral NSAIDs - BUSCOPA

HagaZiekenhuis0 个研究点目标入组 128 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•Legally capable and competent to understand the implications of participation in the study and signed informed consent
•Age 18 years or older
•presentation with renal colic confirmed by ultrasound or CT-scan, not responding to oral NSAIDs and therefore admitted to the urological ward for pain medication.

•Pregnancy or lactation
•Known allergy to any of the products used
•Contra-indication for NSAIDs
•Diagnosis other than renal colic
•Patients presenting with a temperature > 38.5°C at time of inclusion or <24 hours ago
•Patients with antibiotic for UTI together with urolithiasis or urolithiasis with indication for drainage of the upper urinary tract
•Any of the following conditions:
•- Megacolon
•- Intestinal mechanical stenoses
•- Myasthenia gravis
•- Untreated narrow angle glaucoma
•- Epilepsy
•- Alcohol or drugs intoxication
•- Creatinin clearance < 30 ml/min
•- Atrial fibrillation with heart rate > 100/min
•- Ischemic heart disease
•- Heart failure
•- Severe aortic valve stenosis

发起方