Night Myopia and Dark Focus of Accommodation

Not Applicable

Completed

• Conditions: Dark Focus of Accommodation
• Interventions: Diagnostic Test: Accommodation Measurement

• Registration Number: NCT03358550
• Lead Sponsor: University of Applied Sciences Jena

Brief Summary

Shifts in accommodation at decreasing luminance levels are considered as principle cause for night myopia. Previous studies with laser optometers quantified the dark focus of accommodation up to 3 D. In addition to the measurement of dark focus, the aim of this study was to investigate the influence of an imaginary target at finite distances on the state of accommodation at scotopic luminance.

Detailed Description

Accommodation was measured by using an open-field autorefractor (WAM 5500, GRAND SEIKO). Full corrected right eyes of 39 subjects aged from 18 to 40 years were investigated in this randomized, cross-sectional study. Accommodation measurements in photopic luminance were taken for 6 m of empty field and for optotype fixation at 2 m, 1 m and 0.5 m. At scotopic luminance, dark focus of accommodation was examined directly after darkening and after 10 min of dark adaptation. After adaptation, subjects had to visualize imaginary targets in the four distances while accommodation was measured.

Study Timeline

• Study Start: 2017-02-02
• Primary Completion: 2017-03-23
• Study Completion: 2017-03-23
• Status Verified: 2017-11
• Study First Submitted: 2017-11-26
• Study First Submitted QC: 2017-11-29
• Last Update Submitted: 2017-11-29
• Study First Posted: 2017-11-30
• Last Update Posted: 2017-11-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

• age 18 - 44
• visual acuity at least 0.8 (5/6)

Exclusion Criteria

• medication with an impact on the visual system
• visual disease or disease with an impact on the visual system
• pregnancy or other hormonal variances
• drug usage
• overfatigue at the period of investigation
• mental handicap

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Accommodation in scotopic luminance	Accommodation Measurement	-

Primary Outcome Measures

Name	Time	Method
Shift of accommodation in scotopic luminance (Dark focus)	Baseline only	Accommodative shift in scotopic luminance compared to photopic luminance for empty field (dark focus of accommodation)

Secondary Outcome Measures

Name	Time	Method
Difference of accommodation for 2 m target	Baseline only	Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 2 m
Difference of accommodation for 1 m target	Baseline only	Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 1 m
Difference of accommodation for 0.5 m target	Baseline only	Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 0.5 m

Trial Locations

Locations (1)

University of Applied Sciences; 🇩🇪 Jena, TH, Germany