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Epidemiological Study of Fabry Disease in Taiwan Young Stroke Patients

Conditions
Fabry Disease
Interventions
Genetic: GLA gene
Registration Number
NCT03596398
Lead Sponsor
Chiayi Christian Hospital
Brief Summary

Epidemiological Study of Fabry Disease in Taiwan Young Stroke Patients

Detailed Description

This is a cross-sectional, population-based study. No randomization procedure will be executed in this study. Approximately 1000 subjects over a 36-month period. The aim of this screening study is to identify the Fabry disease as the cause in patients with young stroke.

To measure the level of α-Gal A activity, male subjects will initially provide a DBS sample and female subjects will start with a test by whole blood sample.

The prevalence of Fabry disease among patients with young stroke will be estimated by a confirmative diagnosis in gene testing.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
1000
Inclusion Criteria
  • Patients aged 20 or over
  • Patients aged under 56 years old, not included 56
  • Patients with acute stroke
  • Patients and/or their legal representatives are willing to provide written informed consent
Exclusion Criteria
  • Patients with a confirmed diagnosis of Fabry disease

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Young strokeGLA genePatients with acute stroke aged 20 or over, and under 56 years old (Not included 56) .
Primary Outcome Measures
NameTimeMethod
Fabry disease3 years later

The prevalence of Fabry disease in patients with young stroke

Secondary Outcome Measures
NameTimeMethod
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