Epidemiological Study of Fabry Disease in Taiwan Young Stroke Patients

• Conditions: Fabry Disease

• Registration Number: NCT03596398
• Lead Sponsor: Chiayi Christian Hospital

Brief Summary

Epidemiological Study of Fabry Disease in Taiwan Young Stroke Patients

Detailed Description

This is a cross-sectional, population-based study. No randomization procedure will be executed in this study. Approximately 1000 subjects over a 36-month period. The aim of this screening study is to identify the Fabry disease as the cause in patients with young stroke.

To measure the level of α-Gal A activity, male subjects will initially provide a DBS sample and female subjects will start with a test by whole blood sample.

The prevalence of Fabry disease among patients with young stroke will be estimated by a confirmative diagnosis in gene testing.

Study Timeline

• Study Start: 2016-01-01
• Study First Submitted: 2018-06-15
• Status Verified: 2018-07
• Study First Submitted QC: 2018-07-20
• Last Update Submitted: 2018-07-20
• Study First Posted: 2018-07-23
• Last Update Posted: 2018-07-23
• Primary Completion: 2021-09-30
• Study Completion: 2022-01-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Patients aged 20 or over
• Patients aged under 56 years old, not included 56
• Patients with acute stroke
• Patients and/or their legal representatives are willing to provide written informed consent

Exclusion Criteria

• Patients with a confirmed diagnosis of Fabry disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fabry disease	3 years later	The prevalence of Fabry disease in patients with young stroke