The effect of gemifloxacin in treatment of H.pylori infectio
Phase 3
- Conditions
- Dyspepsia.Dyspepsia
- Registration Number
- IRCT201310221155N17
- Lead Sponsor
- Guilan Univercity of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 182
Inclusion Criteria
New cases of H.pylori infection; patients between 18 to 80 years old
Exclusion criteria: The pregnant and brest feeding women; gastric and esophagial malignancies; pylor stenosis; iiver cirrhosis; opium addicts; hypersensitivity to amoxicillin; bismuth subsalicylate; pantoprazole; clarythromycin; gemifloxacin; using cholestyramine; renal failure; history of sizzure; favism and hematologic disorders; incomplete treatment (under 80%); consent to continue treatment; history of H.pylori treatment
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Helicobacter pylori eradication. Timepoint: 12 weeks. Method of measurement: Ureas Breath Test with C14.
- Secondary Outcome Measures
Name Time Method Comparision of two quadriple regimen amoxicillin, bismuth subsalicylate, pantoprazole, clarythromycin and amoxicillin, bismuth subsalicylate, pantoprazole, gemifloxacin in eradication of H.pylori infection. Timepoint: 8-12 weeks. Method of measurement: UBT.