Comparison of different deep venous thrombosis pharmacological prophylaxis in paraplegic patients due to spinal cord injury an exploratory trial
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- To compare efficacy of ASPIRIN , DABIGATRAN AND RIVAROXABAN which can be used as DVT prophylaxis in paraplegic patient with spinal cord injury using components of ultrasound examination of vein viz grey scale ( whether there is compression or not ) and doppler ( whether there is colour filling or not ) using CFV , SFV and popliteal vein screening
研究概览
简要总结
Direct oral anticoagulants (DOACs) have been found to be more effective in recent research, particularly when used in orthopedic populations or as a preventative measure in rehabilitation centers.
Anticoagulants are one of the most important medication which are always prescribed in paraplegic patients to avoid one of the most dreadest complication i.e. DVT. Today we have options of antiplatelets ( like COX inhibitors , PDE inhibitors , ADP P2Y12 antagonist , GP IIB/IIIA anatgonist ) and anticoagulants (vit K inhibitor , factor Xa inhibitor , direct thrombin inhibitors , indirect thrombin inhibitors).
There is lacunae in use of these medications in paraplegic patients due to spinal cord injury and also there effects in blood prameters like D-dimer , ESR and CRPH.
Nevertheless, there are currently not enough data on SCI populations to support more suggestions. In this study we want to screen for deep venous thrombosis in paraplegic patients (whether its present or not ) using components of ultrasound examination of vein viz grey scale ( whether there is compression or not ) and doppler ( whether there is colour filling or not ) using CFV , SFV and popliteal vein screening
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 0.00 Day(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with ASIA A neurology ASIA B neurology FRENKEL A neurology FRENKEL B neurolog.
排除标准
- 未提供
结局指标
主要结局
To compare efficacy of ASPIRIN , DABIGATRAN AND RIVAROXABAN which can be used as DVT prophylaxis in paraplegic patient with spinal cord injury using components of ultrasound examination of vein viz grey scale ( whether there is compression or not ) and doppler ( whether there is colour filling or not ) using CFV , SFV and popliteal vein screening
时间窗: at 14 days , 45 days , 90 days postoperatively
次要结局
- To study cost effective analysis between aspirin , dabigatran , rivaroxaban in paraplegic patient due to spinal cord injury(To study effect of aspirin , dabigatran and rivaroxaban over CRPH , D-dimer , ESR)
研究者
Utsav anand
AIIMS Rishikesh