Efficacy and Safety of Apremilast in Psoriasis
- Registration Number
- NCT06032858
- Lead Sponsor
- Ghurki Trust and Teaching Hospital
- Brief Summary
Psoriasis is a long standing inflammatory, autoinflammatory disease linked with many comorbidities. Patients with moderate to severe plaque psoriasis can be managed with topical as well as systemic medications. FDA approved Apremilast as first drug to be taken orally in cases of psoriasis in mid 1990's. Currently, according to researchers best knowledge no study has been done on use of Apremilast in Pakistan. It has recently become available here. Keeping in view all the benefits of this drug, a study has been planned to check its effectiveness and safety 30mg twice a day, in patients with moderate to severe chronic plaque psoriasis based on Psoriasis area and severity index and Body surface area assessments in our population.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- Diagnosed patients of chronic plaque psoriasis
- patients applicant for oral or parenteral treatments and for light therapy
- patients not responding to topical treatments
- Patients who show hypersensitive reactions to apremilast to any of its inactive component
- Pregnancy
- Lactating mothers
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Apremilast 30 mg twice daily Apremilast 30mg -
- Primary Outcome Measures
Name Time Method Psoriasis area and severity index 16 weeks body surface area 16 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ghurki Hospital
🇵🇰Lahore, Punjab, Pakistan