跳至主要内容
临床试验/CTRI/2024/01/061240
CTRI/2024/01/061240招募中不适用

Anti osteoporotic treatment :Assessing the adherence to pharmacologic treatment in clinical practice

Stavya Spine Hospital and Research Institute1 个研究点 分布在 1 个国家目标入组 385 人开始时间: 2024年1月13日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
385
试验地点
1
主要终点
1.Adherence rates to the drug regimens prescribed

研究概览

简要总结

Osteoporosis causes over 8.9 million fractures annually.“Silent Diseases” like osteoporosis pose a challenge in terms of patient adherence to treatment regimen because the patients do not experience the benefit of symptom reduction. Personal assessment of the disease status drives the patient’s motivation for adherence to the medication regimen. Thus the adherence rates for asymptomatic disease treatments are typically low, being around 50% at end of 1 year.

Previous studies have claimed that adherence to prescribed treatment regimens in osteoporosis declined sharply after diagnosis with persistent falls over subsequent years.Good adherence has been defined as greater than 80% use of the prescribed medications.The beneficial effects of medication compliance can be observed with as little as 50% adherence and are even greater with at least 75-80% adherence

We wish to assess the rates of adherence of patients to the prescribed treatment regimens for anti-osteoporotic drugs and to identify and evaluate the reasons for the non-adherence to any treatment regimens.

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • DEXA proven osteoporotic patients (T score less than-2.5) Patients with history of fragility fractures Patients consenting for participation in the study.

排除标准

  • Patients not fulfilling inclusion criteria.
  • Patients not consenting for participation.

结局指标

主要结局

1.Adherence rates to the drug regimens prescribed

时间窗: patients will be followed up for a period of 2 years from the point of enrollment in the study.The patients will be scheduled for follow up at 3,6,12,18 and 24 months.

2.In case of defaulters, reasons for discontinuation of the drug

时间窗: patients will be followed up for a period of 2 years from the point of enrollment in the study.The patients will be scheduled for follow up at 3,6,12,18 and 24 months.

次要结局

未报告次要终点

研究者

发起方
Stavya Spine Hospital and Research Institute
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Bharat R Dave

Stavya Spine Hospital And Research Institute

研究点 (1)

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