Effects of exercise timing throughout a day of prolonged sitting on blood glucose regulatio

Not Applicable

Recruiting

• Conditions: Obesity; Type 2 diabetes; Metabolic and Endocrine - Metabolic disorders; Metabolic and Endocrine - Diabetes; Diet and Nutrition - Obesity

• Registration Number: ACTRN12616000616471
• Lead Sponsor: Professor John Hawley

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Sedentary overweight or obese [body mass index (BMI) > 25 kg/m2 but < 45 kg/m2] adults with a familial history of type 2 diabetes (diagnosis in a first or second degree relative).

Exclusion Criteria

Pregnancy, use of carbohydrate or lipid-lowering medication, major illness/injury (acute or chronic), current smoker or use of nicotine replacement therapy or physical or major illness/physical problems (acute or chronic) that may limit their ability to participate in the intervention.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood glucose area under the curve (using continuous glucose monitoring systems)[The duration of the intervention (~48 h monitoring period)]

Secondary Outcome Measures

Name	Time	Method
Plasma triglyceride area under the curve[Blood samples from hourly time points (and one time point 30 minutes following each meal) across laboratory visits (Day 2: 0800 h to 1900 h, Day 3: 0800 h to 1600 h)];Plasma insulin area under the curve[Blood samples from hourly time points (and one time point 30 minutes following each meal) across laboratory visits (Day 2: 0800 h to 1900 h, Day 3: 0800 h to 1600 h)];Appetite scores for hunger and satiety measured using a visual analogue scale on a laptop (composite outcome)[Every two hours during laboratory visits]