A Pilot MRI Study of Osteopathic Manipulative Treatment of Acute Low Back Pain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- MRI T2 signal changes
研究概览
简要总结
This is a pilot project intended to determine the feasibility of detecting soft tissue changes in response to osteopathic manipulative treatment (OMT). MRIs of the lumbar and pelvic regions of low back pain (LBP) patients will be taken once before and at two different time points after OMT. Images obtained will be quantitatively analyzed for changes in the volumes of back muscles and for changes (T2 signals) indicative of activity levels or pathological conditions. Electromyography (EMG) will be used as an independent measure of back muscle activity for comparison with MRI results.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (18-55)
- •Patients with LBP with acute symptoms (within last 3 weeks)
- •Test positive for lumbar somatic dysfunction
排除标准
- •History of any spinal injuries/surgeries
- •Positive findings of frank neurological signs during physical exam
- •Any other orthopedic or neurological impairment
- •Unsuitable for MRI imaging:
- •Cardiac pacemaker or defibrillator
- •Severe Claustrophobia
- •Injured by a metallic object that was not removed
- •Cochlear (ear) implants
- •Surgery involving a metallic implant (e.g. knee replacement)
- •Weight more than 300 lbs/136 kg (weight limit for scanner bed)
研究组 & 干预措施
MOT
Treatment will focus on the thoracolumbar junction, L5, the sacrum, and the pubes. Treatment will primarily utilize two techniques, muscle energy and ligamentous-articular release, but will be tailored to the findings of the individual patient.
干预措施: osteopathic manipulative treatment (Other)
结局指标
主要结局
MRI T2 signal changes
时间窗: within 72 hours
次要结局
- MRI anatomic changes and EMG changes(within 72 hours)