ACTRN12622000920796招募中2 期
A prospective randomised, double-blind, placebo-controlled pilot study of the effect of ketamine for adjunct analgesia therapy on opioid requirements in adult mechanically ventilated patients
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 125
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 79 Years（—）
- 性别
- All
入选标准
- •Equal to or greater than 18 years of age
- •Mechanically ventilated at the time of assessment for eligibility
- •Opioid medication infusion prescribed by treating intensive care unit physician
- •Enrolment to occur within the first 12 hours of intensive care unit admission
排除标准
- •Cardiac surgical patients
- •Previous adverse reaction to ketamine
- •Equal to or older than 80 years of age
- •Pregnancy or lactation
- •Uncontrolled hypertension defined as systolic blood pressure of greater than 180 millimeters of mercury
- •Uncontrolled heart failure
- •Patients admitted to intensive care for end-of-life care or to facilitate organ donation
- •Previous enrolment in the KALME trial
- •No legal surrogate identified or able to provide informed consent to continue for patient
研究者
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