NCT00241072已完成4 期
A Single Center, Open Label, Single Arm Trial To Evaluate The Effect Of Twenty Four Weeks Of Treatment With 80 Mg To 320 Mg Valsartan On Insulin Sensitivity In Subjects With Impaired Glucose Tolerance (Igt)
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- Novartis
- 入组人数
- 27
- 主要终点
- Change from baseline insulin sensitivity after 24 weeks
研究概览
简要总结
THE PURPOSE OF THIS STUDY IS TO DETERMINE IF 24 WEEKS OF TREATMENT WITH VALSARTAN (80 MG - 320 MG) IMPROVES INSULIN SENSITIVITY IN SUBJECTS WITH HIGHER THAN NORMAL GLUCOSE LEVELS USING A TEST CALLED THE EUGLYCEMIC CLAMP.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •history or presenting hypertension Elevated fasting blood glucose levels -
排除标准
- •Pregnancy potential Diabetes mellitus
- •Other criteria apply
结局指标
主要结局
Change from baseline insulin sensitivity after 24 weeks
次要结局
- Change from baseline in the function of cells that line blood vessels after 24 weeks
- Change from baseline in markers of vascular inflammation after 24 weeks
- Adverse events and serious adverse events at each study visit for 24 weeks
- Hematology, blood chemistries, and urine measurements for up to 24 weeks
- Vital signs and physical examinations for up to 24 weeks
研究者
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