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Clinical Trials/NCT05806034
NCT05806034
Recruiting
Not Applicable

Evaluation of Anterior Cruciate Ligament Tears Using Diffusion Tractography

Centre Hospitalier Universitaire, Amiens1 site in 1 country297 target enrollmentDecember 8, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
ACL Injury
Sponsor
Centre Hospitalier Universitaire, Amiens
Enrollment
297
Locations
1
Primary Endpoint
Correlation between anisotropy coefficient and ACL lesion state
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

Knees injuries commonly affect the ACL. French current methodology is based on MRI focused on the knee with morphological sequences (T1, DP fat sat) allowing the study of ACL as follows: No lesion / Partial tear / Complete tear.

The treatment (kinesitherapy, surgery, no intervention) is defined taking into account several factors such as age, knee laxity, physical activity and outcome of the radiology analysis (partial or complete tear). However, if the classification is straightforward in case of complete tear, it is not possible to establish a quantitative impact on the ACL in case of partial tear. As a consequence, the investigators will analyze the anisotropy coefficient with diffusion tractography. Any patient who undergo a posttraumatic knee MRI at the CHU Amiens Picardie will have an appointment at the 3T "Signa" MRI that has the knee-centric diffusion tractography sequence.

Registry
clinicaltrials.gov
Start Date
December 8, 2022
End Date
March 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years old,
  • Patient referred for non-enhanced knee MRI for traumatism.
  • Affiliation to a social security program,

Exclusion Criteria

  • Person under guardianship or curators,
  • Any contraindications to MRI

Outcomes

Primary Outcomes

Correlation between anisotropy coefficient and ACL lesion state

Time Frame: one year

Anisotropy coefficient value is between 0 (isotropic medium) to 1 (fibrillar medium) . Anisotropy coefficient =0 is for total ACL rupture ACL lesion state are No lesion, Partial tear or Complete tear

Anisotropy score after tractography MRI sequence

Time Frame: one day

Anisotropy coefficient value is between 0 (isotropic medium) to 1 (fibrillar medium) . Anisotropy coefficient =0 is for total ACL rupture Anisotropy coefficient between 0 end 0.8 is for partial ACL rupture

Study Sites (1)

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