*Diabetes and vascular complications: normoxia versus hypoxia*

Completed

• Conditions: diabetes mellitus type 2; 10018424

• Registration Number: NL-OMON35263
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2012-12-13
• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Diagnosed with type 2 diabetes mellitus at least 2 years ago

Exclusion Criteria

- Cardiovascular disease
- Hypercholesterolemia and/or subjects on cholesterol-lowering drugs
- Hypertension (>160 mmHg systolic and/or >90 mmHg diastolic pressure) and/or subjects on antihypertensive drugs
- Smoking
- Type I diabetes mellitus
- Older than 65 years
- Subjects with vascular complications due to type 2 diabetes mellitus (e.g. diabetic foot ulcer)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Endothelial function (measured as the flow-mediated dilation (FMD))<br /><br>2) Vascular structure (measured as the intima-media thickness (IMT))<br /><br>3) Metabolic function (measured as insulin resistance)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N/A</p><br>