Analysis of Immediate Urinary Continence Predictors After RS-RARP

Active, not recruiting

• Conditions: Prostate Cancer (Post Prostatectomy); Urinary Continence; Retzius-sparing Robot-assisted Radical Prostatectomy

• Registration Number: NCT06850116
• Lead Sponsor: First Affiliated Hospital of Fujian Medical University

Brief Summary

This study is a retrospective, single-center clinical trial. It aims to retrospectively analyze the immediate postoperative urinary continence recovery in prostate cancer patients who underwent Retzius-sparing robot-assisted radical prostatectomy in the investigators' center. Based on the general conditions of patients, relevant perioperative clinical indicators, and parameters related to the sphincter and prostate gland measured by MRI, it explores the influencing factors of immediate urinary continence recovery after Retzius-sparing robot-assisted radical prostatectomy in prostate cancer patients and constructs a relevant prediction model, thereby providing clinical guidance value for predicting immediate postoperative urinary continence recovery.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-01
• Study First Submitted: 2025-02-24
• Study First Submitted QC: 2025-02-24
• Study First Posted: 2025-02-27
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-01
• Last Update Posted: 2025-04-04
• Primary Completion: 2027-01-01
• Study Completion: 2027-01-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Male
• Target Recruitment: 400

Inclusion Criteria

• Prostate cancer diagnosed by prostate biopsy and underwent Retzius-sparing robot-assisted radical prostatectomy in the investigators' hospital.
• Received plain and contrast-enhanced pelvic or prostate MRI examinations before surgery.
• Eastern Cooperative Oncology Group (ECOG) performance status score between 0 and 1.
• Complete clinicopathological data.
• In good general condition, without infections, autoimmune diseases, hematological diseases or other malignant tumors.
• Complete postoperative follow-up data, with a postoperative follow-up time of no less than 6 months.

Exclusion Criteria

• The patient has surgical contraindications.
• The patient has contraindications for MRI examination.
• Preoperative presence of congenital urinary system malformations, urinary incontinence or severe lower urinary tract symptoms, and with a history of urinary catheter or previous transurethral resection of the prostate (TURP) surgery.
• Having received neoadjuvant treatments that may affect the results of this study, such as radiotherapy or hormonal therapy.
• The patient has other concurrent malignant tumors.
• The patient has delayed extubation (> 14 days).
• The patient's clinical, imaging and pathological data are incomplete or the patient is lost to follow-up.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rate of continence	rate of the preservation of urinary control function at 1 week after postoperative removal of the urinary catheter status	Time Frame: 1 week after postoperative removal of the urinary catheter

Trial Locations

Locations (1)

first hospital affiliated of Fujian medical university; 🇨🇳 Fuzhou, Fujian, China