Model of Predicting Biochemical Recurrence After Radical Prostate Cancer Based on Pre-treatment PSMA PET / MR Image Features
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Prostate Cancer
- Sponsor
- Ruijin Hospital
- Enrollment
- 203
- Locations
- 1
- Primary Endpoint
- 18F-PSMA-1007 PET/MR image parameters
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The purpose of this study is to investigate the predictive value of preoperative 18F-PSMA-1007 PET/MR in the predictive effect of biological recurrence (BCR) after radical prostatectomy (RP) for localized prostate cancer (PCa).
Detailed Description
Construct a predictive model for biochemical recurrence (BCR) in patients after radical prostatectomy using imaging parameters from preoperative 18F-PSMA-1007 PET/MRI, and compare the predictive performance of this model with existing clinical models. Data from three centers will be collected, with datasets from two centers used as the training set for the selection of predictive factors and model construction, while the dataset from the remaining center will serve as the validation set to assess the predictive performance of the model for BCR after prostatectomy.
Investigators
Hu Jiajia
Head of Otolaryngology
Ruijin Hospital
Eligibility Criteria
Inclusion Criteria
- •Age ≥ 18 years
- •Histologically confirmed prostate cancer without other types of malignancy -
Exclusion Criteria
- •1.Surgery or endocrine therapy is performed prior to the examination
Outcomes
Primary Outcomes
18F-PSMA-1007 PET/MR image parameters
Time Frame: Before surgery
Secondary Outcomes
- Biochemical recurrence-free survival time(3 years)