Model of Predicting Biochemical Recurrence After Radical Prostate Cancer Based on Pre-treatment PSMA PET / MR Image Features
- Conditions
- Prostate Cancer
- Interventions
- Other: Observe
- Registration Number
- NCT06604377
- Lead Sponsor
- Ruijin Hospital
- Brief Summary
The purpose of this study is to investigate the predictive value of preoperative 18F-PSMA-1007 PET/MR in the predictive effect of biological recurrence (BCR) after radical prostatectomy (RP) for localized prostate cancer (PCa).
- Detailed Description
Construct a predictive model for biochemical recurrence (BCR) in patients after radical prostatectomy using imaging parameters from preoperative 18F-PSMA-1007 PET/MRI, and compare the predictive performance of this model with existing clinical models. Data from three centers will be collected, with datasets from two centers used as the training set for the selection of predictive factors and model construction, while the dataset from the remaining center will serve as the validation set to assess the predictive performance of the model for BCR after prostatectomy.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 203
- Age ≥ 18 years
- Histologically confirmed prostate cancer without other types of malignancy -
1.Surgery or endocrine therapy is performed prior to the examination
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Shanghai East Hospital, Tongji University School of Medicine Observe Patients diagnosed with prostate cancer undergoing PSMA PET/MR examination prior to surgery.
- Primary Outcome Measures
Name Time Method 18F-PSMA-1007 PET/MR image parameters Before surgery
- Secondary Outcome Measures
Name Time Method Biochemical recurrence-free survival time 3 years
Trial Locations
- Locations (1)
Ruijin Hospital affiliated to Shanghai Jiao Tong University of Medicine
🇨🇳Shanghai, China