Fluorodeoxyglucose-positron emission tomography for avoidance of futile direct laryngoscopies under general anaesthesia with taking of biopsies in patients with suspicion on recurrent laryngeal carcinoma after radiotherapy

Completed

• Conditions: aryngeal carcinoma; Cancer; Laryngeal cancer

• Registration Number: ISRCTN89530459
• Lead Sponsor: Vrije University Medical Centre (VUMC) (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-12
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

1. Patients with clinical suspicion on recurrent laryngeal carcinoma after radiotherapy (without obvious signs of tumour), in whom a direct laryngoscopy under general anaesthesia with taking of biopsies is indicated
2. T2 - T4 laryngeal carcinoma

Exclusion Criteria

1. Aged less than 18 years
2. Pregnancy
3. Radiotherapy within the last four months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of direct laryngoscopies (on a group level) needed to detect (a single) recurrent laryngeal carcinoma.

Secondary Outcome Measures

Name	Time	Method
Key:<br>1. Costs<br>2. Operability of a recurrence<br>3. Surgical margins of the salvage laryngectomy<br>4. Quality of life