Relationship of Endoplasmic Reticulum Stress and Adenoid Diseases

Completed

• Conditions: Adenoiditis Acute Infective

• Registration Number: NCT04583631
• Lead Sponsor: Selcuk University

Brief Summary

Adenoid tissue is a significant organ for the performing of immune systems in children. The Endoplasmic Reticulum (ER), is an organelle needed for the care of a stable function of cells. The purpose of the study was to explore the correlation among ER stress and adenoid tissue disorders and to explain the structure of diseases related to the immune system.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-11-01
• Primary Completion: 2019-08-01
• Study Completion: 2019-08-01
• Study First Submitted: 2020-10-05
• Study First Submitted QC: 2020-10-05
• Study First Posted: 2020-10-12
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-21
• Last Update Posted: 2021-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• Patients with the clinical diagnosis of chronic adenoiditis and adenoid hypertrophy.

Exclusion Criteria

• Systemic diseases
• Other otolaryngological

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation of ER stress and apoptosis with chronic adenoiditis and adenoid hypertrophy	2018-2019 (1 year)	Our primary outcome was to evaluate providing that ER stress and apoptosis reaction performing in chronic adenoiditis and adenoid hypertropy, which is related with the immune system of children.

Trial Locations

Locations (1)

Selcuk University; 🇹🇷 Konya, Selcuklu, Turkey