Relationship of Endoplasmic Reticulum Stress and Adenoid Diseases
Completed
- Conditions
- Adenoiditis Acute Infective
- Interventions
- Procedure: Adenoidectomy surgery
- Registration Number
- NCT04583631
- Lead Sponsor
- Selcuk University
- Brief Summary
Adenoid tissue is a significant organ for the performing of immune systems in children. The Endoplasmic Reticulum (ER), is an organelle needed for the care of a stable function of cells. The purpose of the study was to explore the correlation among ER stress and adenoid tissue disorders and to explain the structure of diseases related to the immune system.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
- Patients with the clinical diagnosis of chronic adenoiditis and adenoid hypertrophy.
Exclusion Criteria
- Systemic diseases
- Other otolaryngological
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Chronic adenoiditis Adenoidectomy surgery Patients with hypertrophy and those out of hypertrophy were determined and those who had purulant rhinorrhea signs and rate of adenoids-choana below 50% were categorized that chronic adenoiditis. Adenoid hypertrophy Adenoidectomy surgery Patients who have snoring and those whose adenoid choana rate is greater than 50% were categorized that adenoid hypertrophy group.
- Primary Outcome Measures
Name Time Method Correlation of ER stress and apoptosis with chronic adenoiditis and adenoid hypertrophy 2018-2019 (1 year) Our primary outcome was to evaluate providing that ER stress and apoptosis reaction performing in chronic adenoiditis and adenoid hypertropy, which is related with the immune system of children.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Selcuk University
🇹🇷Konya, Selcuklu, Turkey